State Express Transport Corporation operates daily bus services from Chennai Kilambakkam KCBT to various destinations in Tamilnadu, Kerala, Pondicherry, Karnataka, Telengana and Andhra Pradesh. SETC operates various classes of services such as pushback seat Ultra Deluxe service, AC Seater Bus Service, AC Seater cum Sleeper bus service, non AC Seater cum sleeper bus service, AC Sleeper bus service and Volvo AC Multi Axle Bus Service.
Please find below the timetable of SETC bus services toward destinations, updated with first and last bus timings.
| S.No | Destination | First Bus Time | Last Bus Time |
| 1 | Trichy | 4:30 AM | 11:59 PM |
| 2. | Karaikudi | 6:15 AM | 10:30 PM |
| 3. | Dindigul | 5:00 PM | 10:45 PM |
| 4. | Palani | 7:50 PM | 10:35 PM |
| 5. | Kumbakonam | 5:30 AM | 10:35 PM |
| 6. | Thanjavur | 8:01 AM | 11:30 PM |
| 7. | Salem | 5:00 AM | 11:35 PM |
| 8. | Coimbatore | 9:00 AM | 10:45 PM |
| 9. | Madurai | 4:00 AM | 10:45 PM |
| 10. | Trivandrum – Kerala | 4:30 PM | 4:30 PM |
| 11. | Marthandam | 2:15 PM | 8:00 PM |
| 12. | Nagercoil | 4:15 PM | 9:15 PM |
| 13. | Kanyakumari | 4:30 PM | 9:30 PM |
| 14. | Tirunelveli | 10:00 AM | 10:30 PM |
| 15. | Thoothukudi | 1:30 PM | 10:40 PM |
| 16. | Tiruchendur | 4:30 PM | 08:00 PM |
| 17. | Shencottah | 5:00 PM | 10:00 PM |
The bus service can be booked in advance of 90 days from the date of booking by visiting www.tnstc.in or by visiting computerised ticketing centres in SETC Bus Stand and TNSTC Bus Stands.
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